Anthony Letai received his MD and PhD at the University of Chicago. His PhD was done under the supervision of Elaine Fuchs. Dr. Letai then completed clinical training in Internal Medicine at Brigham and Women's Hospital, Boston. Following this, he completed fellowship in Hematology and Oncology at Dana-Farber Cancer Institute. He was introduced to apoptosis and BCL-2 family proteins as a post-doctoral researcher in the laboratory of the late Stanley Korsmeyer.